Article
The dialectics of cancer: A theory of the initiation and development of cancer through errors in RNAi.
Medical hypotheses - 1 Jan 2006
Wynter Coral V A
Abstract excerpt
The recent discoveries of the RNA-mediated interference system in cells could explain all of the known features of human carcinogenesis. A key, novel idea, proposed here, is that the cell has the ability to recognise a mutated protein and/or mRNA. Secondly, the cell can generate its own short interfering RNA (siRNA) using an RNA polymerase to destroy mutated mRNA, even when only a single base pair in the gene has...
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