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Article

Structure of the mitochondrial editosome-like complex associated TUTase 1 reveals divergent mechanisms of UTP selection and domain organization.

Journal of molecular biology - 11 Jun 2010

Stagno Jason, Aphasizheva Inna, Bruystens Jessica, Luecke Hartmut, Aphasizhev Ruslan

Abstract excerpt

RNA uridylylation reactions catalyzed by terminal uridylyl transferases (TUTases) play critical roles in the formation of the mitochondrial transcriptome in trypanosomes. Two mitochondrial RNA editing TUTases have been described: RNA editing TUTase 1 catalyzes guide RNA, ribosomal RNA, and mRNA 3'-uridylylation, and RNA editing TUTase 2 acts as a subunit of the RNA editing core complex (also referred to as the...

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Source

Open in PubMed Open full text

Identifiers

PMID: 20403364
DOI: 10.1016/j.jmb.2010.04.021
PMCID: PMC2916031

Genes

TUT4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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Structure of the mitochondrial editosome-like complex associated TUTase 1 reveals divergent mechanisms of UTP selection and domain organization.PMID 20403364Read ↗

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