Article
The 14 bp deletion-insertion polymorphism in the 3' UT region of the HLA-G gene influences HLA-G mRNA stability.
Human immunology - 1 Nov 2003
Rousseau Philippe, Le Discorde Magali, Mouillot Gaël, Marcou Céline, Carosella Edgardo D, Moreau Philippe
Abstract excerpt
Human leukocyte antigen (HLA)-G molecules are generated by an alternative splicing of the primary transcript of the gene and display specialized function in regulating the immune response. Although HLA-G gene polymorphism is low, it may influence levels of protein expression and, in some cases, has been associated with pregnancy diseases. The HLA-G gene exhibits 14 alleles generating six proteins with minor...
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