Article
Case-control study of a HLA-G 14-bp insertion-deletion polymorphism in women with recurrent miscarriages.
Scandinavian journal of immunology - 1 Jan 2010
Zhu Y, Huo Z, Lai J, Li S, Jiao H, Dang J, Jin C
Abstract excerpt
Human leucocyte antigen (HLA)-G is an important molecule for maintaining an immunotolerant foetal-maternal relationship. A 14-bp insertion (+14-bp)/deletion (-14-bp) polymorphism in exon 8 of the 3' untranslated region of the HLA-G gene has been proposed to be associated with HLA-G mRNA stability and the expression of HLA-G. This might play an immunomodulatory role in human pregnancy. In this study, a total of...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
