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Article

A single base-pair mutation in the 3'-untranslated region of HLA-G mRNA is associated with pre-eclampsia.

Molecular human reproduction - 1 Nov 2008

Yie Shang-mian, Li Liang-hong, Xiao Rong, Librach Clifford L

Abstract excerpt

Human leukocyte antigen-G (HLA-G) is a non-classical class I HLA molecule that is expressed by extravillous cytotrophoblast cells. This protein may play a critical role in the protection of cytotrophoblasts from maternal immune response, allowing these semi-allogeneic cells to invade the uterus unimpeded. We have demonstrated that diminished placental HLA-G expression is associated with pre-eclampsia. In order to...

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Source

Identifiers

PMID: 18952696
DOI: 10.1093/molehr/gan059

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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A single base-pair mutation in the 3'-untranslated region of HLA-G mRNA is associated with pre-eclampsia.PMID 18952696Read ↗

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The 3'-untranslated region of the HLA-G gene in relation to pre-eclampsia: revisited.Semantic proximity Read ↗

The + 3010/C single nucleotide polymorphism (rs1710) at the HLA-G 3' untranslated region is associated with a short transcript exhibiting a deletion of 92 nucleotides.Semantic proximity Read ↗

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The 14 bp deletion-insertion polymorphism in the 3' UT region of the HLA-G gene influences HLA-G mRNA stability.Semantic proximity Read ↗

The expression and functional activity of membrane-bound human leukocyte antigen-G1 are influenced by the 3'-untranslated region.Semantic proximity Read ↗

Association of genetic variants in the 3'UTR of HLA-G with Recurrent Pregnancy Loss.Semantic proximity Read ↗

Simple methods for the detection of HLA-G variants in coding and non-coding regions.Semantic proximity Read ↗

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A combination of single nucleotide polymorphisms in the 3'untranslated region of HLA-G is associated with preeclampsia.Semantic proximity Read ↗

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HLA-G polymorphisms and molecule function--questions and more questions--a review.Semantic proximity Read ↗

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