Article
Expression of PTEN in renal cell carcinoma and its relation to tumor behavior and growth
29 Oct 2003
Abstract excerpt
BACKGROUND AND OBJECTIVES: PTEN is a candidate tumor suppressor gene in a variety of malignant tumors, including renal cell carcinoma (RCC). PTEN regulates cell cycle progression and cell survival in vivo. However, the role of PTEN alterations and their association with tumor growth and behavior in patients with RCC has not been well established. The aim of our study was to evaluate PTEN expression in RCC and its...
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