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Article

Loss of PTEN expression is associated with metastatic disease in patients with endometrial carcinoma

15 Apr 2002

Abstract excerpt

BACKGROUND: The PTEN tumor suppressor gene frequently is involved in endometrial carcinoma. Loss of heterozygosity and mutations reportedly are common, although the biologic importance of these changes remain largely unknown. The objective of this study was to assess the pattern of PTEN expression by immunohistochemistry in a large series of patients with endometrial carcinoma. METHODS: A population-based series...

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Identifiers

PMID: 12001116
DOI: 10.1002/cncr.10434

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Loss of PTEN expression is associated with metastatic disease in patients with endometrial carcinomaPMID 12001116Read ↗

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Loss of PTEN expression is an independent predictor of favourable survival in endometrial carcinomasSemantic proximity Read ↗

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PTEN methylation is associated with advanced stage and microsatellite instability in endometrial carcinoma.Semantic proximity Read ↗

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Altered PTEN Expression as a Diagnostic Marker for the Earliest Endometrial PrecancersSemantic proximity Read ↗

[Detection of mutation and protein expression of PTEN gene in endometrial carcinoma].Semantic proximity Read ↗

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