Article
Loss of Expression of PTEN is Associated with Worse Prognosis in Patients with Cancer.
Asian Pacific journal of cancer prevention : APJCP - 1 Jan 2015
Qiu Zhi-Xin, Zhao Shuang, Li Lei, Li Wei-Min
Abstract excerpt
BACKGROUND: The tumor suppressor phosphatase and tensin homolog (PTEN) is an important negative regulator of cell-survival signaling. However, available results for the prognostic value of PTEN expression in patients with cancer remain controversial. Therefore, a meta-analysis of published studies investigating this issue was performed. MATERIALS AND METHODS: A literature search via PubMed and EMBASE databases...
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