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Article

Enhanced activity of human serotonin transporter variants associated with autism.

Philosophical transactions of the Royal Society of London. Series B, Biological sciences - 27 Jan 2009

Prasad Harish C, Steiner Jennifer A, Sutcliffe James S, Blakely Randy D

Abstract excerpt

Rare, functional, non-synonymous variants in the human serotonin (5-hydroxytryptamine, 5-HT) transporter (hSERT) gene (SLC6A4) have been identified in both autism and obsessive-compulsive disorder (OCD). Within autism, rare hSERT coding variants associate with rigid-compulsive traits, suggesting...

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Identifiers

PMID: 18957375
DOI: 10.1098/rstb.2008.0143
PMCID: PMC2674096

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-18957375-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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