Article
Common and rare alleles of the serotonin transporter gene, SLC6A4, associated with Tourette's disorder.
Movement disorders : official journal of the Movement Disorder Society - 1 Aug 2013
Moya Pablo R, Wendland Jens R, Rubenstein Liza M, Timpano Kiara R, Heiman Gary A, Tischfield Jay A, King Robert A, Andrews Anne M, Ramamoorthy Samanda, McMahon Francis J, Murphy Dennis L
Abstract excerpt
To evaluate the hypothesis that functionally over-expressing alleles of the serotonin transporter (SERT) gene (solute carrier family 6, member 4, SLC6A4) are present in Tourette's disorder (TD), just as we previously observed in obsessive compulsive disorder (OCD), we evaluated TD probands (N = 151) and controls (N = 858). We genotyped the refined SERT-linked polymorphic region 5-HTTLPR/rs25531 and the associated...
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