Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

[Respective weight of genotypes DQA1 and DQB1 associated with insulin-dependent diabetes in French children].

Diabete & metabolisme - 1 Jan 2000

Fajardy I, Levy-Marchal C, Gu X F, Krishnamoorthy R, Elion J, Czernichow P

Abstract excerpt

Genetic susceptibility alleles have been identified at the DQ HLA region. The aim of the present study was to confirm the value of these markers, and to evaluate the respective weight in the risk of the different alleles at the DQA1 and DQB1 levels, identified by restriction mapping after polymerase chain reaction on exon 2. A significant enrichment in DQB1 alleles encoding for an aminoacid different from...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adolescent
Share to Alleles
Share to Child

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Child, Preschool

Share to Gene Frequency

Share to Genetic Markers

Share to Genotype

Share to Risk Factors

Source

Identifiers

PMID: 1459318

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

[Respective weight of genotypes DQA1 and DQB1 associated with insulin-dependent diabetes in French children].PMID 1459318Read ↗

Comparison between HLA-DRB and DQ DNA sequences and classic serological markers as type 1 (insulin-dependent) diabetes mellitus predictive risk markers in the Spanish population.Semantic proximity Read ↗

Prevalence of HLA-DQ beta chain non-Asp alleles in type I (insulin-dependent) diabetics with young and older ages of onset.Semantic proximity Read ↗

Susceptibility to type 1 (insulin-dependent) diabetes mellitus in Spanish patients correlates quantitatively with expression of HLA-DQ alpha Arg 52 and HLA-DQ beta non-Asp 57 alleles.Semantic proximity Read ↗

HLA-DQA1 and DQB1 alleles in French and Algerian type 1 diabetic subjects.Semantic proximity Read ↗

[DQA1 and DQB1 HLA genes as markers of insulin-dependent diabetes mellitus in the Polish population].Semantic proximity Read ↗

[Polymorphism of HLA-DQA1 and DQB1 genes in the Moscow population and in patients with diabetes mellitus types 1 and 2].Semantic proximity Read ↗

HLA-DQB 1 codon 57 and genetic susceptibility to type 1 (insulin-dependent) diabetes mellitus in French children.Semantic proximity Read ↗

Reevaluation of the importance of polymorphic HLA class II alleles and amino acids in the susceptibility of individuals of different populations to type I diabetes.Semantic proximity Read ↗

Increased and decreased relative risk for non-insulin-dependent diabetes mellitus conferred by HLA class II and by CD4 alleles.Semantic proximity Read ↗

Similarity of HLA-DQ profiles in adult-onset type 1 insulin-dependent diabetic patients with and without extra-pancreatic auto-immune disease.Semantic proximity Read ↗

Assessment of the DQB1-DQA1 complete genotype allows best prediction for IDDM.Semantic proximity Read ↗

Complementation of HLA-DQA and -DQB genes confers susceptibility and protection to insulin-dependent diabetes mellitus.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.