Isolation and characterization of a brefeldin A-resistant mutant of monkey kidney Vero cells.

doi:10.1016/0014-4827(92)90005-s

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Article

Isolation and characterization of a brefeldin A-resistant mutant of monkey kidney Vero cells.

Experimental cell research - 1 Dec 1992

Chen C H, Kuwazuru Y, Yoshida T, Nambiar M, Wu H C

Abstract excerpt

Brefeldin A (BFA) is a fungal antibiotic which disrupts protein transport between the endoplasmic reticulum and the Golgi. A BFA-resistant mutant of monkey kidney Vero cells, BER-40, which exhibited about a 90-fold increase in the LD50 of BFA (5.2 ng/ml for Vero cells versus 460 ng/ml for BER-40...

Topics

Adenosine Triphosphate
Animals
Antifungal Agents
Azides
Brefeldin A
Cyclopentanes
Deoxyglucose
Drug Resistance
Genes, Dominant
Golgi Apparatus
Mannosidases
Mutation
Proteins
Ricin
Sodium Azide
Vero Cells

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