Article
Nucleoside transport-deficient mutants of PK-15 pig kidney cell line.
Biochimica et biophysica acta - 21 Sept 1992
Aran J M, Plagemann P G
Abstract excerpt
Previous studies indicated that PK-15 pig kidney cells express solely a nitrobenzylthioinosine-sensitive, equilibrative nucleoside transporter. In the present study, PK-15 cells were mutagenized by treatment with ICR-170 and nucleoside transport-deficient mutants selected in a single step in growth medium containing tubercidin and cytosine arabinoside at a frequency of about 2 x 10(6). The mutants were...
Topics
- Animals
- Biological Transport
- Carrier Proteins
- Cell Division
- Cell Line
- Clone Cells
- Cytarabine
- DNA
- Escherichia coli
- Flow Cytometry
- Floxuridine
- Hypoxanthine
