Article
Verotoxin-resistant cell clones are deficient in the glycolipid globotriosylceramide: differential basis of phenotype.
Archives of biochemistry and biophysics - 1 May 1991
Pudymaitis A, Armstrong G, Lingwood C A
Abstract excerpt
Escherichia coli-derived verotoxin is an extremely toxic protein and is highly selective toward certain primate cells. Two susceptible cell lines are the Daudi cell line (human Burkitt lymphoma) and the Vero cell line (Green African monkey kidney). Both of these cell lines contain significant levels of the verotoxin binding glycolipid globotriosylceramide (Gb3) (1 nmol/10(7) cells and 3 nmol/10(6) cells,...
Topics
- Animals
- Bacterial Toxins
- Burkitt Lymphoma
- Cell Line
- Cell Survival
- Cytotoxins
- Galactosyltransferases
- Glycolipids
- Humans
- Phenotype
- Shiga Toxin 1
- Trihexosylceramides