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Article

Abnormal osmotic regulation in trpv4-/- mice.

Proceedings of the National Academy of Sciences of the United States of America - 11 Nov 2003

Liedtke Wolfgang, Friedman Jeffrey M

Abstract excerpt

Osmotic homeostasis is one of the most aggressively defended physiological parameters in vertebrates. However, the molecular mechanisms underlying osmotic regulation are poorly understood. The transient receptor potential channel, vanilloid subfamily (TRPV4), is an osmotically activated ion channel that is expressed in circumventricular organs in the mammalian CNS, which is an important site of osmotic sensing....

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Share to TRPV Cation Channels
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 14581612
DOI: 10.1073/pnas.1735416100
PMCID: PMC263876

Genes

TRPV4
FOS

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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