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Article

Na(x)-deficient mice show normal vasopressin response to dehydration.

Neuroscience letters - 26 Mar 2010

Nagakura Ayano, Hiyama Takeshi Y, Noda Masaharu

Abstract excerpt

In dehydrated animals, the antidiuretic hormone vasopressin (VP) is released from the nerve terminals of magnocellular neurons of the supraoptic nucleus (SON) and paraventricular nucleus (PVN) into the systemic circulation at the posterior pituitary. Increases in sodium (Na+)-level and osmolality in body fluids upon dehydration are reportedly sensed by a Na+-sensor and/or an osmosensor, respectively. However, it...

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Identifiers

PMID: 20138121
DOI: 10.1016/j.neulet.2010.01.077

Genes

SON

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