Article
Toward identification of susceptibility genes for sporadic Parkinson's disease.
Journal of neurology - 1 Oct 2003
Toda Tatsushi, Momose Yoshio, Murata Miho, Tamiya Gen, Yamamoto Mitsutoshi, Hattori Nobutaka, Inoko Hidetoshi
Abstract excerpt
To identify susceptibility genes for Parkinson's disease (PD) and to establish tailor-made medicine for PD, we studied 20 single nucleotide polymorphisms (SNPs) in 18 candidate genes for association with PD. We found that homozygosity for the V66M polymorphism of the BDNF gene occurs more frequently in PD patients than in unaffected controls and confirmed an association with the S18Y polymorphism of the UCHL1...
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