Article
Analysis of GWAS-linked loci in Parkinson disease reaffirms PARK16 as a susceptibility locus.
Neurology - 10 Aug 2010
Tan E-K, Kwok H-H, Kwok H-K, Tan L C, Zhao W-T, Prakash K M, Au W-L, Pavanni R, Ng Y-Y, Satake W, Zhao Y, Toda T, Liu J-J
Abstract excerpt
OBJECTIVE: A genome-wide association study (GWAS) in the Japanese population identified 2 new Parkinson disease (PD) susceptibility loci on 1q32 (PARK16) (OMIM 613164) and BST1. We analyzed single nucleotide polymorphism (SNPs) located at the GWAS-linked loci (PARK16, PARK8, PARK1, and BST1) in a Chinese population and also conducted a meta-analysis in Asians by pooling 2 independent replication studies from...
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