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Article

Altered epithelial cell proportions in the fetal lung of glucocorticoid receptor null mice.

American journal of respiratory cell and molecular biology - 1 May 2004

Cole Timothy J, Solomon Nicola M, Van Driel Rosemary, Monk Julie A, Bird Daniel, Richardson Samantha J, Dilley Rodney J, Hooper Stuart B

Abstract excerpt

Glucocorticoids provide important signals for maturation of the fetal lung and antenatal glucocorticoids are used to reduce the respiratory insufficiency suffered by preterm infants. To further understand the role of glucocorticoids in fetal lung maturation, we have analyzed mice with a targeted null mutation for the glucocorticoid receptor (GR) gene, which severely retards lung development. The lungs of fetal...

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Identifiers

PMID: 14578211
DOI: 10.1165/rcmb.2003-0236OC

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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