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Article

Regulation of alveolar epithelial cell phenotypes in fetal sheep: roles of cortisol and lung expansion.

American journal of physiology. Lung cellular and molecular physiology - 1 Dec 2004

Flecknoe Sharon J, Boland Rochelle E, Wallace Megan J, Harding Richard, Hooper Stuart B

Abstract excerpt

Our aim was to determine whether cortisol's effect on alveolar epithelial cell (AEC) phenotypes in the fetus is mediated via a sustained alteration in lung expansion. Chronically catheterized fetal sheep were exposed to 1) saline infusion, 2) cortisol infusion (122-131 days' gestation, 1.5-4.0 mg/day), 3) saline infusion plus reduced lung expansion, or 4) cortisol infusion plus reduced lung expansion. The...

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Identifiers

PMID: 15298856
DOI: 10.1152/ajplung.00375.2003

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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