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Article

Glucocorticoid Receptor Regulates Overlapping and Differential Gene Subsets in Developing and Adult Skin

30 Sept 2010

Abstract excerpt

We have previously shown that the glucocorticoid receptor (GR) is required for skin homeostasis and epidermal barrier competence. To understand the transcriptional program by which GR regulates skin development, we performed a microarray analysis using the skin of GR(-/-) and GR(+/+) mice of embryonic d 18.5 and identified 442 differentially expressed genes. Functional clustering demonstrated overrepresentation...

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Identifiers

PMID: 20880987
DOI: 10.1210/me.2010-0183

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