Article
Human alcoholism studies of genes identified through mouse quantitative trait locus analysis.
Addiction biology - 1 Oct 2002
Ehringer Marissa A, Thompson Jessica, Conroy Otakuye, Goldman David, Smith Tom L, Schuckit Marc A, Sikela James M
Abstract excerpt
Coding region DNA sequence variants have been recently identified in several QTL candidate genes in a mouse model of differential sensitivity to alcohol [inbred long-sleep (ILS) and inbred short-sleep (ISS)]. This work has been extended into a human population characterized for their initial level of response to alcohol (LR). The coding region of one of the most promising of these candidate genes, zinc finger 133...
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