Confirmation of quantitative trait loci for ethanol sensitivity in long-sleep and short-sleep mice.

doi:10.1101/gr.7.2.92

Back to search

Article

Confirmation of quantitative trait loci for ethanol sensitivity in long-sleep and short-sleep mice.

Genome research - 1 Feb 1997

Markel P D, Bennett B, Beeson M, Gordon L, Johnson T E

Abstract excerpt

Initial insensitivity to alcohol is a strong predictor of human alcoholism, a widespread and heritable health problem. The Long Sleep and Short Sleep lines of mice were developed by genetic selection for high or low alcohol sensitivity. We have identified seven quantitative trait loci (QTLs) spec...

Topics

Alcoholic Intoxication
Alcoholism
Animals
Chromosome Mapping
Epistasis, Genetic
Ethanol
Female
Genes
Genetic Linkage
Genetic Markers
Genetic Variation
Genome
Humans
Male
Mice
Mice, Inbred Strains
Mice, Mutant Strains
Polymorphism, Genetic

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.