Article
Quantitative trait locus analysis.
Alcohol research & health : the journal of the National Institute on Alcohol Abuse and Alcoholism - 1 Jan 2000
Grisel J E
Abstract excerpt
Alcoholism is a quantitative disorder that is caused by the combined influences of numerous genes (i.e., quantitative trait loci [QTLs]) and environmental factors. To identify QTLs for alcoholism, researchers compare subject groups (e.g., inbred mouse strains) that differ in both their genetic makeup (i.e., genotype) and alcohol-related trait (e.g., sensitivity to certain alcohol effects). Using statistical tests...
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