Article
Tbx5 is essential for heart development.
Development (Cambridge, England) - 1 Apr 1999
Horb M E, Thomsen G H
Abstract excerpt
Mutations in the Tbx5 transcription factor cause heart septal defects found in human Holt-Oram Syndrome. The complete extent to which Tbx5 functions in heart development, however, has not been established. Here we show that, in Xenopus embryos, Tbx5 is expressed in the early heart field, posterio...
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