Article
The Arg16Gly polymorphism of the beta2-adrenergic receptor and left ventricular systolic function.
American journal of hypertension - 1 Nov 2003
Tang Weihong, Devereux Richard B, Kitzman Dalane W, Province Michael A, Leppert Mark, Oberman Albert, Hopkins Paul N, Arnett Donna K
Abstract excerpt
BACKGROUND: beta-Adrenergic receptors (ARs), including beta1- and beta2-AR, are involved in modulation of cardiac contractility and heart rate. Arg16Gly, a functional polymorphism in the beta2-AR gene, has been reported to influence exercise capacity in heart failure patients. This study examined...
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