Article
The Arg16/Gly beta2-adrenergic receptor polymorphism is associated with altered cardiovascular responses to isometric exercise.
Physiological genomics - 13 Feb 2004
Eisenach John H, McGuire Antonio M, Schwingler Rachel M, Turner Stephen T, Joyner Michael J
Abstract excerpt
A polymorphism in the gene encoding the beta(2)-adrenergic receptor (arginine or glycine at amino acid position 16) is associated with altered vasodilator responses to beta(2)-agonists, which may modulate the pressor response to endogenous catecholamines during stress. To test the hypothesis that the Arg16/Gly polymorphism is associated with differences in acute pressor responses to sympathoexcitation, we...
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