Article
No evidence for involvement of IL-4R and CD11B from the IBD1 region and STAT6 in the IBD2 region in Crohn's disease.
European journal of human genetics : EJHG - 1 Nov 2003
de Jong Dirk J, Franke Barbara, Naber Anton H J, Willemen Judith J H T, Heister Angelien J G A M, Brunner Han G, de Kovel Carolien G F, Hol Frans A
Abstract excerpt
Linkage studies have identified the inflammatory bowel disease (IBD)1 locus on chromosome 16 and the IBD2 locus on chromosome 12 to be involved in Crohn's disease. NOD2/CARD15 was identified as the gene of interest within the IBD1 region. However, linkage to this region could not be explained by NOD2/CARD15 alone. Here we set out to assess the association of additional candidate genes from the IBD1 and IBD2 loci...
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