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Article

Crohn's disease associated CARD15 (NOD2) variants are not involved in the susceptibility to type 1 diabetes.

Molecular genetics and metabolism - 1 Nov 2005

Ghandil Pegah, Chelala Claude, Dubois-Laforgue Danièle, Senée Valérie, Caillat-Zucman Sophie, Kockum Ingrid, Luthman Holgar, Nerup Jorn, Pociot Flemming, Timsit José, Julier Cécile

Abstract excerpt

Three variants in the caspase recruitment domain 15/nucleotide-binding oligomerization domain 2 (CARD15/NOD2) gene have been shown to be associated with Crohn's disease (CD). There is a strong support for shared genetic determinants between various autoimmune and inflammatory diseases. In particular, linkage of type 1 diabetes (T1D) and other autoimmune and inflammatory diseases has been reported on chromosome...

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Source

Identifiers

PMID: 16198136
DOI: 10.1016/j.ymgme.2005.07.029

Genes

NOD2
INS

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

Related research

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Research trail→

Click a neighbor to travelStep 1 · 12 closest

Crohn's disease associated CARD15 (NOD2) variants are not involved in the susceptibility to type 1 diabetes.PMID 16198136Read ↗

CARD15/NOD2 single nucleotide polymorphisms do not confer susceptibility to type I psoriasis.Semantic proximity Read ↗

CARD4/NOD1 is not involved in inflammatory bowel disease.Semantic proximity Read ↗

NOD2/CARD15 gene mutation is not associated with susceptibility to Wegener's granulomatosis.Semantic proximity Read ↗

CARD15/NOD2 mutations in Crohn's disease.Semantic proximity Read ↗

NOD2/CARD15 disease associations other than Crohn's disease.Semantic proximity Read ↗

No evidence for involvement of IL-4R and CD11B from the IBD1 region and STAT6 in the IBD2 region in Crohn's disease.Semantic proximity Read ↗

CARD15/NOD2 gene variants are associated with familially occurring and complicated forms of Crohn's disease.Semantic proximity Read ↗

NOD2/CARD15 and TNFA, but not IL1B and IL1RN, are associated with Crohn's disease.Semantic proximity Read ↗

Analysis of CARD15/NOD2 haplotypes fails to identify common variants associated with rheumatoid arthritis susceptibility.Semantic proximity Read ↗

Absence of mutation in the NOD2/CARD15 gene among 483 Japanese patients with Crohn's disease.Semantic proximity Read ↗

NOD2/CARD15 gene polymorphisms are not associated with collagenous colitis.Semantic proximity Read ↗

Alterations of the CARD15/NOD2 gene and the impact on management and treatment of Crohn's disease patients.Semantic proximity Read ↗

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