Article
Genetics of inflammatory bowel disease: progress and prospects.
Human molecular genetics - 1 Apr 2004
Mathew Christopher G, Lewis Cathryn M
Abstract excerpt
Strong epidemiological evidence for a genetic contribution to pathogenesis in inflammatory bowel disease (IBD) has stimulated efforts to identify susceptibility genes for both of its major clinical forms, Crohn's disease and ulcerative colitis. Genome scans for linkage have indicated multiple regions of interest, but replication of these has been limited. The detection of linkage on chromosome 16 (IBD1) led to...
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