Article
Progress towards identifying inflammatory bowel disease susceptibility genes.
Novartis Foundation symposium - 1 Jan 2004
Rioux John D
Abstract excerpt
Genomewide searches have identified about a dozen genomic regions potentially containing inflammatory bowel disease (IBD) susceptibility loci. Although some were observed in more than one genome scan or in replication studies, no one locus has been identified in all studies. This apparent lack of consistency is explained by the modest effect of most genetic loci in complex traits and by the modest power and the...
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