Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Stratification by CARD15 variant genotype in a genome-wide search for inflammatory bowel disease susceptibility loci.

Human genetics - 1 Nov 2003

Shaw Sarah H, Hampe Jochen, White Ray, Mathew Christopher G, Curran Mark E, Schreiber Stefan

Abstract excerpt

Previously we have conducted a genome-wide search for inflammatory bowel disease susceptibility loci in a large European cohort. Results from this study demonstrated suggestive evidence of linkage to loci at chromosomes 1q, 6p, and 10p and replicated linkages on chromosomes 12 and 16. Recently, NOD2/CARD15 on chromosome 16q12 has been found to be strongly associated with Crohn's disease. In order to determine if...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Apoptosis Regulatory Proteins
Share to CARD Signaling Adaptor Proteins

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Carrier Proteins

Share to DNA Mutational Analysis

Share to Inflammatory Bowel Diseases

Share to Intracellular Signaling Peptides and Proteins

Share to Nod2 Signaling Adaptor Protein

Share to Pedigree

Source

Identifiers

PMID: 13680363
DOI: 10.1007/s00439-003-1020-7

Genes

NOD2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Stratification by CARD15 variant genotype in a genome-wide search for inflammatory bowel disease susceptibility loci.PMID 13680363Read ↗

The IBD6 Crohn's disease locus demonstrates complex interactions with CARD15 and IBD5 disease-associated variants.Semantic proximity Read ↗

Advances in the genetics of inflammatory bowel disease.Semantic proximity Read ↗

The role of genetics in inflammatory bowel disease.Semantic proximity Read ↗

CARD15/NOD2 risk alleles in the development of Crohn's disease in the Australian population.Semantic proximity Read ↗

Characterization of genotype-phenotype relationships and stratification by the CARD15 variant genotype for inflammatory bowel disease susceptibility loci using multiple short tandem repeat genetic markers.Semantic proximity Read ↗

Investigation of NOD1/CARD4 variation in inflammatory bowel disease using a haplotype-tagging strategy.Semantic proximity Read ↗

Molecular genetics of Crohn's disease.Semantic proximity Read ↗

Significant role of genetics in IBD: the NOD2 gene.Semantic proximity Read ↗

Association of NOD2 (CARD 15) genotype with clinical course of Crohn's disease: a cohort study.Semantic proximity Read ↗

The molecular classification of the clinical manifestations of Crohn's disease.Semantic proximity Read ↗

Genetics of inflammatory bowel disease: progress and prospects.Semantic proximity Read ↗

CARD15/NOD2 mutations in Crohn's disease.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.