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Article

Insertional mutation in the intron 1 of Unc5h3 gene induces ataxic, lean and hyperactive phenotype in mice.

Experimental animals - 1 Jul 2003

Choi Yoon Sik, Hong Seung-Beom, Jeon Hee Kyung, Kim Eun Ju, Oh Wan-Jae, Joe So-Young, Han Jin Soo, Lee Min-Jae, Lee Han-Woong

Abstract excerpt

Mice carrying a mutation in the first intron of Unc5h3 were accidentally produced by transgenic insertion and characterized for their homozygous mutant phenotypes. Morphological and histological analysis revealed cerebellar and midbrain abnormalities, which are similar to the previously reported phenotypes of the Unc5h3 mutant. Behavioral analysis showed higher ambulatory activity and circling, and defects in...

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Identifiers

PMID: 14562603
DOI: 10.1538/expanim.52.273

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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