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Article

Behavioural characterization of AnkyrinG deficient mice, a model for ANK3 related disorders.

Behavioural brain research - 15 Jun 2017

van der Werf I M, Van Dam D, Missault S, Yalcin B, De Deyn P P, Vandeweyer G, Kooy R F

Abstract excerpt

ANK3 encodes AnkyrinG (AnkG), a member of the Ankyrin family that is expressed in several different isoforms in many tissues. A unique serine-rich domain and tail domain in the two largest isoforms of AnkG (270 and 480kDa), restrict AnkG to the axon initial segment and nodes of Ranvier of myelinated neurons. At these sites, AnkG is a master regulator, coordinating the strict clustering of components necessary for...

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Source

Identifiers

PMID: 28411148
DOI: 10.1016/j.bbr.2017.04.014

Genes

ANK3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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