Article
Interaction of proteins with promoter elements of the human U2 snRNA genes in vivo.
Gene - 2 Oct 2003
Boyd Diana C, Pombo Ana, Murphy Shona
Abstract excerpt
The multicopy human U2 small nuclear (sn)RNA genes are transcribed by RNA polymerase (pol) II and contain two major promoter elements upstream of the transcription start site: an essential proximal sequence element (PSE) at around -55 and a distal sequence element (DSE) at around -220. We have carried out an in vivo footprinting analysis on these genes, and the results suggest that most, if not all, of the U2...
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