Article
Reciprocal interferences between nucleosomal organization and transcriptional activity of the yeast SNR6 gene.
Genes & development - 15 Feb 1995
Marsolier M C, Tanaka S, Livingstone-Zatchej M, Grunstein M, Thoma F, Sentenac A
Abstract excerpt
Recent work has demonstrated a repressive effect of chromatin on the transcription of the yeast SNR6 gene in vitro. Here, we show the relations between chromatin structure and transcriptional activity of this gene in vivo. Analysis of the SNR6 locus by micrococcal nuclease digestion showed a protection of the TATA box, nuclease-sensitive sites around the A and B blocks, and arrays of positioned nucleosomes in the...
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