Article
Basal promoter and enhancer element of yeast U6 snRNA gene.
Journal of molecular biology - 20 Oct 1993
Burnol A F, Margottin F, Schultz P, Marsolier M C, Oudet P, Sentenac A
Abstract excerpt
The yeast U6 snRNA gene, SNR6, transcribed by RNA polymerase III or C, is shown to have a mixed promoter with upstream, intragenic and downstream elements. The distant downstream B block behaves as a typical enhancer element. Required in vivo, and for transcription of chromatin templates in vitro, it was also active in reversed orientation. As shown by footprinting and electron microscopy, the factor TFIIIC, or...
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