Article
Cdm1, the smallest subunit of DNA polymerase d in the fission yeast Schizosaccharomyces pombe, is non-essential for growth and division.
Current genetics - 1 Oct 1998
Reynolds N, Watt A, Fantes P A, MacNeill S A
Abstract excerpt
Highly purified DNA polymerase delta from the fission yeast Schizosaccharomyces pombe is a complex of at least four distinct subunits. Genes encoding three of these (pol3+/cdc6+, cdc1+ and cdc27+) have been characterised previously. Here we describe the isolation and characterisation of cdm1+, the gene encoding the smallest (22kDa) subunit of the Pol delta complex. Over-expression of cdm1+, which encodes a 160...
Topics
- Amino Acid Sequence
- Base Sequence
- Cell Count
- Cell Cycle Proteins
- Cell Division
- Chromosomes
- Cloning, Molecular
- DNA Polymerase III
- Fungal Proteins
- Gene Deletion
- Gene Expression Regulation, Fungal
