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Article

The fission yeast cdc19+ gene encodes a member of the MCM family of replication proteins.

Journal of cell science - 1 Oct 1994

Forsburg S L, Nurse P

Abstract excerpt

We have cloned and characterized the fission yeast cdc19+ gene. We demonstrate that it encodes a structural homologue of the budding yeast MCM2 protein. In fission yeast, the cdc19+ gene is constitutively expressed, and essential for viability. Deletion delays progression through S phase, and cells arrest in the first cycle with an apparent 2C DNA content, with their checkpoint control intact. The...

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Source

Identifiers

PMID: 7876346
DOI: 10.1242/jcs.107.10.2779

Genes

MCM2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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