Article
Nuclear and mitochondrial DNA microsatellite instability in gastrointestinal stromal tumors.
Pathobiology : journal of immunopathology, molecular and cellular biology - 1 Jan 2006
Kose K, Hiyama T, Tanaka S, Yoshihara M, Yasui W, Chayama K
Abstract excerpt
OBJECTIVE: Gastrointestinal stromal tumors (GISTs) are the most common mesenchymal tumors of the digestive tract. Nuclear (nMSI) and mitochondrial microsatellite instability (mtMSI) play important roles in tumorigenesis in various organs. The aim of this study was to evaluate the role of nMSI and mtMSI in GISTs. METHODS: Samples from 74 mesenchymal tumors were collected. nMSI and mtMSI were examined by...
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