Article
Implication of microsatellite instability in human gastric cancers.
The Indian journal of medical research - 1 May 2012
Shokal Upasana, Sharma Prakash C
Abstract excerpt
Microsatellite instability, one of the phenomena implicated in gastric cancer, is mainly associated with the expansion or contraction of microsatellite sequences due to replication errors caused most frequently by mutations in the mismatch repair (MMR) and tumour suppressor genes. Tumours exhibiting microsatellite instability are proven to have truncated products resulting from frequent mutations in...
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