Article
BRAF and KRAS mutations in stomach cancer.
Oncogene - 9 Oct 2003
Lee Sug Hyung, Lee Jong Woo, Soung Young Hwa, Kim Hong Sug, Park Won Sang, Kim Su Young, Lee Jong Heun, Park Jik Young, Cho Yong Gu, Kim Chang Jae, Nam Suk Woo, Kim Sang Ho, Lee Jung Young, Yoo Nam Jin
Abstract excerpt
Ras proteins control signaling pathways that are key regulators of several aspects of normal cell growth and malignant transformation. BRAF, which encodes a RAF family member in the downstream pathway of RAS, is somatically mutated in a number of human cancers. The activating mutation of BRAF is known to play a role in tumor development. As there have been no data on the BRAF mutation in stomach cancer, we...
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