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Article

Mutations of BRAF and KRAS2 in the development of Barrett's adenocarcinoma.

Oncogene - 15 Jan 2004

Sommerer Florian, Vieth Michael, Markwarth Annett, Röhrich Knut, Vomschloss Susanne, May Andrea, Ell Christian, Stolte Manfred, Hengge Ulrich R, Wittekind Christian, Tannapfel Andrea

Abstract excerpt

Activation of the Raf/MEK/ERK (MAPK) signal transduction cascade by RAS mutations has been found in a variety of human cancers. Mutations of BRAF provide an alternative route for activation of this signalling pathway. To determine the role of mutations in BRAF and KRAS2 in the neoplastic progress...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 14724583
DOI: 10.1038/sj.onc.1207189

Genes

BRAF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-14724583-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

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