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Article

Sequencing analysis of BRAF mutations in human cancers.

Methods in enzymology - 1 Jan 2006

Wooster Richard, Futreal Andrew P, Stratton Michael R

Abstract excerpt

Cancers arise because of the accumulation of mutations in critical genes that alter normal programs of cell proliferation, differentiation, and death. The RAS-RAF-MEK-ERK-MAP kinase pathway mediates cellular responses to growth signals. RAS is mutated to an oncogenic form in approximately 15% of...

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Share to BRAF gene
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Proto-Oncogene Proteins B-raf

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Source

Identifiers

PMID: 16757326
DOI: 10.1016/S0076-6879(05)07018-7

Genes

BRAF
ARAF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-16757326-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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