A genetic variant in the gene encoding the stress70 protein chaperone family member STCH is associated with gastric cancer in the Japanese population.

doi:10.1016/j.bbrc.2005.07.110

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A genetic variant in the gene encoding the stress70 protein chaperone family member STCH is associated with gastric cancer in the Japanese population.

Biochemical and biophysical research communications - 23 Sept 2005

Aoki Masayuki, Yamamoto Ken, Ohyama Shigekazu, Yamamura Yoshitaka, Takenoshita Seiichi, Sugano Kokichi, Minamoto Toshinari, Kitajima Masaki, Sugimura Haruhiko, Shimada Shinya, Noshiro Hirokazu, Hiratsuka Masahiro, Sairenji Motonori, Ninomiya Itasu, Yano Masahiko, Uesaka Katsuhiko, Matsuno Seiki, Maehara Yoshihiko, Aikou Takashi, Sasazuki Takehiko

Abstract excerpt

Association analysis, based on linkage disequilibrium between specific alleles in the candidate loci and nearby genetic markers, has been proposed to identify genes conferring susceptibility to multifactorial diseases. Using the affected sib-pair method, we previously mapped four candidate chromosomal regions, 1p32, 2q33-q35, 11p13-p14, and 21q21, for gastric cancer by linkage analysis. To identify genes involved...

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PMID: 16087163
DOI: 10.1016/j.bbrc.2005.07.110

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