Article
Differential processing of stromal-derived factor-1alpha and stromal-derived factor-1beta explains functional diversity.
Blood - 1 Apr 2004
De La Luz Sierra Maria, Yang Fuquan, Narazaki Masashi, Salvucci Ombretta, Davis David, Yarchoan Robert, Zhang Hongwei H, Fales Henry, Tosato Giovanna
Abstract excerpt
The chemokine stromal-derived factor-1 (SDF-1), which is constitutively expressed in most tissues as SDF-1alpha and SDF-1beta resulting from alternative gene splicing, regulates hematopoiesis, lymphocyte homing, B-lineage cell growth, and angiogenesis. Because SDF-1alpha and SDF-1beta are constit...
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