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Article

Comodulation of CXCR4 and CD26 in human lymphocytes.

The Journal of biological chemistry - 1 Jun 2001

Herrera C, Morimoto C, Blanco J, Mallol J, Arenzana F, Lluis C, Franco R

Abstract excerpt

We provide convergent and multiple evidence for a CD26/CXCR4 interaction. Thus, CD26 codistributes with CXCR4, and both coimmunoprecipitate from membranes of T (CD4(+)) and B (CD4(-)) cell lines. Upon induction with stromal cell-derived factor 1alpha (SDF-1alpha), CD26 is cointernalized with CXCR4. CXCR4-mediated down-regulation of CD26 is not induced by antagonists or human immunodeficiency virus (HIV)-1 gp120....

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Share to Chemokine CXCL12
Share to Chemokines, CXC
Share to Adenosine Deaminase

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Dipeptidyl Peptidase 4

Share to Pertussis Toxin

Share to Pseudopodia

Share to Receptors, CXCR4

Share to Virulence Factors, Bordetella

Source

Identifiers

PMID: 11278278
DOI: 10.1074/jbc.M004586200

Genes

CXCR4
ADA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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