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Article

Identification of a ribavirin-resistant NS5B mutation of hepatitis C virus during ribavirin monotherapy.

Hepatology (Baltimore, Md.) - 1 Oct 2003

Young Kung-Chia, Lindsay Karen L, Lee Ki-Jeong, Liu Wen-Chun, He Jian-Wen, Milstein Susan L, Lai Michael M C

Abstract excerpt

Ribavirin (RBV), a guanosine analogue, has been suggested to exert an antiviral action against hepatitis C virus (HCV) by causing lethal mutations and suppressing RNA polymerase in vitro, but the mechanism of its clinical therapeutic effects is currently unknown. To test the hypothesis that RBV c...

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Source

Identifiers

PMID: 14512874
DOI: 10.1053/jhep.2003.50445

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-14512874-2026-09-02.1. Manifest publication-graph-cohort-2026-09-02.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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Identification of a ribavirin-resistant NS5B mutation of hepatitis C virus during ribavirin monotherapy.PMID 14512874Read ↗

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