Article
Detection of factor V Leiden by PCR-SSCP using GMA precast Elchrom scientific gels.
Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis - 1 Jul 2003
Simundic Ana-Maria, Topic Elizabeta, Stefanovic Mario
Abstract excerpt
Genetic abnormalities in hemostatic proteins associated with hypercoagulability are an important hereditary risk factor for venous thrombosis. Several genetic mutations that cause hereditary disorders predisposing to thrombosis have been described, point mutation in the coagulation factor V gene (FV:R506Q), called factor V Leiden, being the most common of them. A new inexpensive and simple polymerase chain...
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