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Article

Hydrolink gels: a rapid and simple approach to the detection of DNA mutations in thromboembolic disease.

Journal of clinical pathology - 1 Feb 1992

Perry D J, Carrell R W

Abstract excerpt

AIMS: To develop a simple and rapid technique for detecting DNA mutations based on the polymerase chain reaction, followed by electrophoresis, in a novel polymer--Hydrolink D5000--specifically designed to separate double stranded DNA fragments. METHODS: Eleven subjects with previously characterised mutations within the antithrombin gene (including single base pair mutations and insertions) and three normal...

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Identifiers

PMID: 1541698
DOI: 10.1136/jcp.45.2.158
PMCID: PMC495664

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Source receipt: pubmed, retrieved 7 Sept 2026.

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